wrinkle filler

Wrinkle Filler 101

Dermal fillers for facial wrinkles are a huge business in the United States. In fact, researchers are already working on the next generation of fillers, which may include a solid, threadlike filler.

This new type of solid state hyaluronic acid filler is less painful.

The research, presented at the annual meeting of the American Society of Plastic Surgeons in Denver, was conducted in South America on patients seeking treatment for crow’s feet and forehead wrinkles.

Touted as one of the wrinkle fillers, it is about as thin as a strand of hair and not technically an injectable.

dermal filler

Instead it’s placed with a needle into a facial line. Shortly after insertion, the thread becomes hydrated and morphs into a gel. Doctors involved in the study said it was easier and faster to place compared to injectable face fillers and patients reported less pain.

The filler can be placed in the exact depth and position desired without spreading and is more predictable than other treatments. That should allow for better results filling finer lines around the mouth, around the eyes, and long, linear creases.

This means consumers can have their forehead wrinkles removed and maintain forehead expression, which is currently prevented by the typical treatment paradigm of paralysis using a neurotoxin or Botox.


If misplaced, the material can be removed. It is expected to have the same safety profile as hyaluronic acid gel and last about the same amount of time. More long term studies will be needed before the product can really advance to the marketplace, although this advanced type of deep wrinkle filler has already been available since 2013.

Injectable wrinkle fillers can give you a more youthful look for a fraction of what a traditional face lift costs.

wrinkle filler
Instant Results

Most will fill lines and wrinkles in less than 30 minutes with results that can last from four months to more than a year.

An injectable deep wrinkle filler, unlike Botox injections that relax the muscle under a wrinkle, fill the line or crease with one of several different substances. As a result, the line or crease seems to have nearly disappeared.

Fillers can also be used as “volumizers” and the filler plumps and lifts the cheeks, filling out thin lips, and plumping sagging hands. The treatment is fast and easy.

Not every wrinkle is right for every type of filler

The least risks and best results come from using the best wrinkle filler correctly. That’s one reason why you should only have wrinkle fillers injected by a board-certified dermatologist or plastic surgeon.


Hyaluronic Acid Wrinkle Fillers

The most popular category of wrinkle filler is hyaluronic acid. Each type of hyaluronic acid wrinkle filler works in a slightly different way with varying results. Some research shows that repeated injections may help stimulate the body’s own natural production of collagen. That will help reduce the number of lines and wrinkles. There is also some evidence that less filler is needed over time to achieve the same look.

Hyaluronic wrinkle fillers include:

Gel made of hyaluronic acid

Effects can last up to one year for moderate to severe facial wrinkles and folds. It is not recommended if you have severe allergies, particularly if you’re allergic to bacterial proteins

Hyaluronic acid particles suspended in a gel

Effects can last up to six months or longer for moderate to severe wrinkles and folds. It is not recommended if you have severe allergies.


Synthetic  Wrinkle Fillers

This smaller category of wrinkle fillers includes lab-made substances that are not related to anything found naturally in the skin. The benefits of this category include a longer-lasting effect and one filler offers permanent filling of lines and creases. A one-time instant wrinkle filler is less likely to cause side effects.

Synthetic fillers include:

Calcium hydroxylapatite suspended in gel

Effects last typically one year and research shows that the body begins producing collagen around the micro-spheres, which might lead to longer lasting effects over time. This can be used for long-lasting fill of deep lines, including folds around the nose.

Synthetic poly-L-lactic acid

Effects last typically up to one year. It is used in volumizing for HIV patients suffering from loss of facial structure. The ingredients in this filler are made for deep injections below the muscles and not for injecting into fine lines.


Collagen Based Wrinkle Fillers

One of the best deep wrinkle filler developed was made from a purified form of collagen extracted mostly from cows. Although it worked well and offered a natural looking line and crease fill, the results may vary depending on the patient. New ways of processing the collagen have helped reduce risks. In addition, new forms of synthetic collagens are making these injections safer and more useful for a wider range of people.

Collagen fillers include:

Collagen made from purified human tissue grown in a lab.

This type of collagen filler does not require a skin test. Its effects last up to six months depending on the area that is treated. It is used for frown lines, crow’s feet, forehead lines, vertical lip lines, nose-to-mouth lines, lip border, and scar filling. Cosmoplast is used for deeper, more pronounced wrinkles as well as treating fine lines around the eyes.